Senior Scientist, Discovery Chemistry

Company: Johnson & Johnson
Location: San Diego
Posted on: May 4, 2025

Job Description:

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.comJob Function:Discovery & Pre-Clinical/Clinical DevelopmentJob Sub Function:Chemical ResearchJob Category:Scientific/TechnologyAll Job Posting Locations:San Diego, California, United States of AmericaJob Description:About Innovative Medicine:Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.Learn more at We are searching for the best talent for a Senior Scientist, Discovery Chemistry role to be in San Diego, CA.Purpose:We are seeking an experienced, highly skilled, and motivated analytical and separation scientist to work in our laboratories in La Jolla, CA, for the position of Senior Scientist in Discovery Chemistry. This position will require the candidate to possess and leverage deep knowledge and capabilities in Analytical Chemistry and Separation Sciences as part of the Analytical Chemistry and High Throughput Purification (AC-HTP) team to provide support to discovery chemists. Strong communication skills and the ability to thrive in a team and results oriented environment are key attributes. The candidate must also have strong interpersonal skills to influence in a collaborative multidisciplinary environment.You will be responsible for:

• Applying chiral and achiral chromatography methods and capabilities to accelerate Janssen small molecule discovery research.
• Evaluating and implementing new chromatography methods and apply them across different modalities and/or capabilities, such as small molecule drug discovery, peptide drug discovery, DNA-encoded library, target protein degradation and Direct-to-biology.
• Presenting at internal and external scientific meetings as appropriate.
• Working with the vendors, when needed, to implement new instrumentation and maintain the smooth operation of instruments.
• Routinely interacting with colleagues from therapeutic area project teams and core technology groups to develop and implement strategies on analytical chemistry to help advance programs.Qualifications / Requirements:Education:
  • a minimum of a Masters degree in chemistry or related discipline is requiredRequired:
    • a minimum of 4years industry experience is required
    • Capability in analytical and chromatography method development and optimization to characterize synthetic medicinal compounds is required
    • In-depth knowledge and extensive experience in Analytical and Separation Sciences is required
    • Expert knowledge of modern analytical and purification techniques, such as UPLC/MS and SFC/MS is required
    • Strong problem-solving skills for developing creative, innovative solutions, and meeting project objectives are requiredPreferred:
      • Prior experience on analytical chemistry for beyond Role of 5 molecules is preferred
      • Demonstrated experience with lab automation and high throughput assaying is preferred
      • Demonstrated experience with other analytical chemistry skills, such as NMR data analysis, is preferred
      • Proven track record in chromatography, such as presentations at major conferences and/or publications on peer-reviewed journals, is preferredThe anticipated base pay range for this position is $105,000 - $169,050.The compensation and benefits information set forth in this posting applies to candidates hired in the United States. Candidates hired outside the United States will be eligible for compensation and benefits in accordance with their local market.The Company maintains highly competitive, performance-based compensation programs. Under current guidelines, this position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. The annual performance bonus is a cash bonus intended to provide an incentive to achieve annual targeted results by rewarding for individual and the corporation's performance over a calendar/ performance year. Bonuses are awarded at the Company's discretion on an individual basis.Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance. Employees may be eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)).Employees are eligible for the following time off benefits:
        • Vacation - up to 120 hours per calendar year
        • Sick time - up to 40 hours per calendar year; for employees who reside in the State of Washington - up to 56 hours per calendar year
        • Holiday pay, including Floating Holidays - up to 13 days per calendar year
        • Work, Personal and Family Time - up to 40 hours per calendar yearAdditional information can be found through the link below.For additional general information on Company benefits, please go to:
          • Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center () or contact AskGS to be directed to your accommodation resource.The anticipated base pay range for this position is :$105,000 - $169,050Additional Description for Pay Transparency:
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Keywords: Johnson & Johnson, Rancho Palos Verdes , Senior Scientist, Discovery Chemistry, Other , San Diego, California